Trans-cyclohexane-l,2-diamine

The Mn(n)-catalysed oxidation of glucose by peroxodisulfate ions occius via a radical-chain mechanism. Kinetics of oxidation of thiodiglycoUic acid by (trans-cyclohexane-l,2-diamine-A, A, A, A -tetraacetato)manganate(ni) have been investigated. Oxidations of ketoses and aldoses by manganese(TV) in sulfuric acid media have a first-order dependence on sugar and Iractional-order dependence on oxidant. A mechanism has been proposed for the oxidation of L-mahc acid by Mn(III) pyrophosphate in aqueous acid, involving complex formation and radicals. ... 

ESI-MS, ultraviolet, and NMR were used to study templating effects on the DCLs, and proved that metal ion binding is the driving force. Recently, the same group reported a highly diastereoselective amplification induced by Cd of the heterochiral form of macrocycle 52 starting from a mixture of (R,R)- and (S,S)-trans-cyclohexane-l,2-diamine [56],... 

Diamines. Chromatography has been used to isolate three isomers of trans- and cis-[Co(CN)2 (RR)-cyclohexane-l,2-diamine 2] and five isomers of the corresponding propylenediamine complexes. Mer- and /ac-isomers of tris(meso-pentane-3,4-diamine)cobalt(iii) have been prepared and separated using column chromatography. The rates of aquation of three isomers of [CoCl(tmd)(dien)] and one isomer of [CoCl(tmdXdpt)] have been measured and the kinetic parameters calculated [dpt = NH2(CH2)3NH(CH2)3NH2, tmd = NH2(CH2)3NH2]. The interaction of [Co(dien)2] with sulphate, thiosulphate, sulphite, selenite, tellurite, and carbonate ions has been studied potentiometrically and stability constants determined for the outer-sphere complexes. The i.r. spectrum of octahedral... 

Sterically more demanding copper(II) chelates based on trans-cyclohexane-1,2-diamine reveal similar condensation chemistry [165]. The yield of macrocyclic products, however, decreases compared to the reaction with ethane-1,2-diamine-containing chelates. The formation of copper(II) complexes of half-capped ligands is favoured compared to capped species for steric reasons. The presence of two asymmetric carbon atoms in the starting ligson allows synthesis of new chiral macrocycles. The most suitable for macrocyclisation has proved to be the R,R S,S bis(cyclohexane-l,2-diamine)copper(II). The three isomers of H2LI36 possible... 

Dach-Pt ds-Dihydroxo(cyclohexane-trans-L-l,2-diamine)platinum II... 

The KR of racemic amines bearing more than one stereocenter is also challenging, and lipases have acted with a high level of stereodiscrimination in combinahon with nonactivated esters. For instance, the CAL-B-catalyzed resolution of trans-2-phenyl-cyclopentanamine with EtOAc proceeds with an excellent enantioselectivity, while the reaction with cis-2-phenylcyclopentanamine led to poorer results (E = 16 and 28% conversion) [205]. Nevertheless, this problem has been overcome using other acyl donors such as racemic ds-2-phenylcyclopentyl methoxyacetate (Figure 9.28). This strategy can be also successfully used for the resolution of frans-2-phenylcyclohexan-amine [206], frans-N-substituted-cyclopentane-l,2-diamines [207, 208], trans-N-substituted-cyclohexane-1,2-diamines, [209] and c/s-cyclohex-4-ene-l,2-diamine [210]. 

In a similar way, other derivatives of diamines (S,S)-28 and (R,R)-29 were evaluated for their gelation properties. As an example, trans-(R,R) 1,2-bis(dodecy-lureido)cyclohexane and trans-(R,R)-1,2-bis(octadecylureido)cyclohexane can cause physical gelation in a wide variety of organic solvents [76]. As an extension of these studies, novel polymerizable organogelators based on tra s-(7 ,7 )-l,2-bis(ur-eido)cyclohexane derivatives have been reported [77]. In these molecules, the presence of methacrylate-functionalized carboxylic acid groups determines the... 

A distorted octahedral, deep red complex of 1,2-diamine (R,R )-trans-l,2-bis(N-pyrrolidino)cyclohexane (L), L-0s04 has been made at low temperatures.103 It is very reactive and is formally a 20e outer valence shell species. The isolation of this and relevant 1,2-diamine complexes throws light upon the mechanism of enantiose-lective dihydroxylation of alkenes noted below. The tetroxide has important commercial use in the stoichiometric and catalytic cis-hydroxylation of alkenes. There has been much discussion of the mechanism, particularly for the enantiospecificity achieved in the presence of cinchona alkaloids or other chiral agents.104... 

Ohya, Y., Masunaga, T., Baba, T., Ouchi, T., 1996, Synthesis and cytotoxic activity of dextran carrying cis-dichloro(cyclohexane-trans-l-1,2-diamine) platinum(II) complex. J. Biomater. Sci. PolymerEdn. 7 1085-1096. 

H Cis(trans)-l,2-cyclohexane- diamine" -2e Cis(trans)-1,2-cyclohexane-diamine... 

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