Tranquilizers physiological effects

Beneficial physiological effects of the major and minor tranquilizers include ... 

Benzodiazepines have been rather overshadowed by the isomeric 1,4-benzodiazepines, which have been of enormous pharmacological interest, largely because of their very wide use as tranquilizers. Some 1,5-benzodiazepines also have physiological effects, inter alia, some 2-amino-4-phenyl derivatives as tranquilizers (80FES181) and some 2-p-fluorophenyl-... 

The effects of GHB on sleep have been well documented. Even small doses produce relaxation, tranquillity, and drowsiness. A sufficiently high dose of GHB will induce sudden sleep within 5 to 10 minutes. Although other sedative-hypnotics interfere with various stages of the sleep cycle and prevent the body from achieving complete and balanced rest, GHB-induced sleep seems to closely resemble normal physiological sleep.42 In a clinical study, GHB has been shown to induce sleep rapidly without suppressing REM sleep, thereby improving sleep quality.43... 

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