Toxicity Testing in the 21st Century

US-NAS (2007) Toxicity testing in the 21st century a vision and a strategy. National Academies Press, Washington DC... 

Kavlock RJ, Austin CP, Tice R (2009) Toxicity testing in the 21st century, implications for human health risk assessment. Risk Anal 29 485 87... 

Andersen ME, Krewski D (2010) The vision of toxicity testing in the 21st century moving from discussion to action. Toxicol Sci 117(1) 17-24... 

Another level of enhanced effort will be in the area of epidemiology, both traditional and molecular, and human in vitro research in support of the identification of key events in humans and of the human relevance of an animal MoA. The recently published National Research Council (NRC) Report, Toxicity Testing in the 21st Century A Vision and a Strategy (NRC 2007), provides a set of research options for enhancing the use of in vitro test systems with an emphasis on human cells. This... 

NRC (2007). Toxicity Testing in the 21st Century A Vision and a Strategy, Board on Environmental Studies and Toxicology (BEST), Institute for Laboratory Animal Research (ILAR), National Research Council of the National Academies, Washington, D.C., http //books.nap.edu/openbook.php record id= 11970 page=Rl. 

Meek, B., and Doull, J. (2009). Pragmatic challenges for the vision of toxicity testing in the 21st century in a regulatory context Another Ames test . .. or a new edition of the Red Book Toxicol Sci 108, 19-21. 

NRC (2007b). Toxicity Testing in the 21st Century A Vision and a Stategy, National Academies Press, Washington, D.C., pp. 1-196. 

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