Topological Distribution of Metastatic Cells as Analyzed by Whole-Body Autoradiography

Topological Distribution of Metastatic Cells as Analyzed by Whole-Body Autoradiography 

B16BL6 cells were incubated in the presence of 3.7 MBq of [ I]IUDR for 4 h. The cells were washed and harvested with EDTA-phosphate-buffered saline (PBS), and suspended in medium. [ I]IUDR-labeled B16BL6 cells (1 x 10 cells) were intravenously injected into C57BL/6 mice via a tail vein. Animals were sacrificed at 15 and 120 min after injection, and frozen immediately with 

---