Tools Useful for the Analysis of Ganglioside Functions

Later (see Chapter 7), the roles of gangliosides in transmembrane signaling and in cell-cell recognition will be discussed in detail. Also, the quite recent 

Acquotti, D., Fronza, G., Riboni, L., Sonnino, S., and Tettamanti, G., 1987, Ganglioside lactones H-NMR determination of the inner ester position of GDlb-ganglioside lactone naturally occurring in human brain or produced by chemical synthesis, Glycoconjugate J. 4 119-127. 

and Yu, R. K., 1978, High performance thin-layer chromatography and densitometric determination of brain ganglioside compositions of several species. Anal. Bio-chem. 89 437-450. 

Scarsdale, J. N., Kusunoki, S., and Prestegard, J. H., 1989, High resolution proton NMR studies of gangliosides. Structure of two types of GD3 lactones and their reactivity with monoclonal antibody R24, J. Biol. Chem. 264 3478-3483. 

Hirabayashi, Y, Kon, K., Inagaki, F., Tate, S., and Whittaker, V. P., 1992, A tri-sialoganglioside containing a sialyla2-6-N-acetylgalactosamine residue is a cholinergic-specific antigen, J. Biochem. 111 287-290. 

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