Tonantzitlolone

Alkene Metathesis in Total Synthesis Valienamine, Agelastatin and Tonantzitlolone... 

Applications to natural product synthesis probe the limits of any synthetic method, as situations arise that would never have been considered in the course of first developing the method. Recent syntheses of valienamine 6, agelastatin 9 and tonantzitlolone 15 pressed the limits of ring-closing metathesis. 

Tebbe reaction 148 Tetracyclin synthesis 190 Tetrazole synthesis 17 Tetrodotoxin synthesis 136 Tocopherol synthesis 142 Tonantzitlolone synthesis 188 Triazine synthesis 17 Triclavulone synthesis 102... 

---