Toluene 5-nitro-2-nitroso

Note Cycle acid , which is weaker than mixed acid is used for starting the nitration in order not to allow the reaction to become too violent and to be able to more easily control the temp during the early stages of nitration. The compn of the "cycle acid is similar to that used in the mononitration of toluene, such as H2SO4 53 5, HNO3 7.2, Nitroso 15 0 nitro bodies 1.0%, which was listed by Clift Fedoroff in "A Manual for Explosives Laboratories , Vol 1, Chap III, p 2(1942)... 

Azido, nitramino, nitro and nitroso derivatives are listed under what may be considered as the parent compound. Thus all the mono-, di-, and trinitrotoluenes will be discussed under toluene. For example, nitraminoterrazoles are discussed under aminotetrazole. With this system the various azido, nitro, etc derivatives included above are kept together and are not scattered throughout the Encyclopedia. Since these derivatives of a given parent compound are usually of some related interest from the point of view of properties, preparation and references, we believe tbat this arrangement is the most convenient... 

Another side reaction which occurs is reduction in the reaction the —N2C1 or —N(NO)COCH3 group is replaced by hydrogen. wi-Bromo-toluene was isolated in 6% yield from the reaction between the sodium diazotate from 2-bromo-4-methylaniline and benzene, and in 10% yield in a similar reaction from 2-methyl-4-bromoaniline.4 Some nitrobenzene is obtained in the preparation of 3-nitrobiphenyl from nitroso-w-nitro-acetanilide (p. 250). The source of the hydrogen effecting the reduction has not been determined. f... 

Essentially the same transformation can be conducted on a more highly substituted steroid. The required nitroso ester can in principle be prepared from reaction of DHEA 3-acetate (6-1) with bromine and nitrous acid (Scheme 3.6). The reaction sequence would start by addition of bromine from the open a-side of the steroid to form bromonium ion 6-2. Attack on that ion by the nitroso anion from the [3 side together with the rule of diaxial opening of a three-membered ring will the lead to formation of the nitrite 6-3. Irradiation of a toluene solution of the nitrite ester with a mercury vapor lamp walks the nitro group across the gap, in effect functionalizing C19. Heating the initially formed nitroso dimer in propan-... 

TOLUENE-a,a-DIOL, 0-NITRO-, DI-ACETATE, 36, S8 -NITRO-, DIACETATE, 36, S8 -TOLUENESULFENYL CHLORIDE, 35, 99 -TOLUENESULFINYL CHLORIDE, 34, 93 -Toluenesulfonamide, N-methyl-N-nitroso-, 34, 24, 96 -Toluenesulfonic acid, 30, 30, 31 monohydrate, 36, 92 38, 37... 

Nitroso-piperidine—Nitro-toluene—Azo-benzene, introduction of hydroxyl groups — Toluene-sulphone-amides— Saccharine—p-Nitro-o-toluene-sulphone - amide—Oxida -tion of aromatic oxy-carboxylic acids.76-78... 

The complexes [react with aromatic nitro compounds in toluene at room temperature same oxo-imido derivatives obtained by reaction with the correspond ng aromatic nitroso derivatives (eq. 21) (53]. This suggests that n i trosobenzenes are intermediates in the conversion o-f nitro compounds to the binuclear metal 0x0 complexes. These complexes by reaction with NaOH under phase trans-fer conditions give the corresponding aromatic ami nes. 

Hansson and Alm [10] have separated diphenylamine, triphenyl-amine and the corresponding nitroso- and nitro derivatives on silica gel 6 layers, using toluene, benzene or chloroform. 

The following compounds were considered, 4,6-dinitroanthranil 2,4,6 trinitrobenzyl alcohol 2,4,6-trinitrobenzaldhyde 2,4,6-trinitrobenzoi acid trinitrobenzene, tetranitroazoxytoTuene 2,4,6-trinitrobenzonitrile picric acid 5-nitroso-2-nitrotoluene 3,5-dinitro-4 amino toluene and 2,4,6-trinitrobenzaldehyde oxime. From a comparison o the spectra it was concluded that benzaldoxime, anthranil and nitrile ar being produced. Compounds such as trinitrobenzaldehyde, trinitrolbenzoi acid and tribenzylalcohol did not show separate peaks from that of nitro... 

Hg(OAc)2 catalyses the nitration of toluene with HNO3 in AcOH at 80 °C, giving 0-, m-, and p-nitrotoluenes in the ratios 3 1 4.3. Other mercury(il) salts give similar results. The reaction occurs in three steps mercuration (rate-limiting), nitrosodemercuration, and oxidation of nitroso- to nitro-toluenes. ... 

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