TNF Effects on Human Glia

TNF also up-regulates intercellular adhesion molecule 1 (ICAM-1) on glial cells and leukocyte functional antigen (LFA)-1)32, but not LFA-la, 

and when combined with IFN-y and IL-ljS, TNF can activate iNOS activity in other human peripheral cell types (Nussler and Billiar, 1993 Rosenkranz-Weiss et al., 1994). 

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