Tissue growth factors becaplermin

Cliuical pharmacology Native PDGF is a growth factor derived from blood platelets that mediates tissue repair. Becaplermin has biological activity similar to that of endogenous PDGF it promotes the chemotactic recruitment and prohfera-tion of cells involved in wound repair— fibroblasts, smooth muscle cells, monocytes, and neutrophils—and enhances the formation of granulation tissue. 

---