Tinea corporis, treatment with

In the case of tinea corporis, treatment may last longer than six weeks. The treatment of onychomycosis may last up to twelve months, certainly if the toenails are involved. Caution is required in patients with impaired kidney or Hver function or hematological disorders. Also, use is contraindicated during pregnancy. 

Figure 5. Tinea corporis caused by Trichophyton sp. (a) before and (b) after topical treatment with bifonazole (one treatment daily for three weeks).

Ledezma E, Lopez JC, Marin P, et al. Ajoene in the topical short-term treatment of tinea cruris and tinea corporis in humans randomized comparative study with terbinafine. Arzneim-Forsch/Drug Res 1999 49 544-547. 

The azoles miconazole (Micatin, others) and econazole (Spectrazole, others) and the allylamines naftifine (Naftin) and terbinafine (Lamisil, others) are effective topical agents for the treatment of localized tinea corporis and uncomplicated tinea pedis. Topical therapy with the azoles is preferred for localized cutaneous candidiasis and tinea versicolor. 

Sulconazole, an imidazole derivative with antifungal effectiveness, is used in the treatment of tinea cruris, tinea corporis, and tinea pedis caused by Trichophyton menta-grophytes, Epidermophyton floccosum, and Microspomm canis. It is also used in the treatment of tinea versicolor caused by Malassezia furfur. 

Tolnaftate is an antifungal agent that distorts hyphae and inhibits mycelial growth in susceptible fungi. It is indicated in the treatment and prophylaxis of tinea pedia (athlete s foot) treatment of tinea cruris (jock itch) or tinea corporis (ringworm) caused by specific fungi treatment of oncho-mycosis, chronic scalp infections, palm and sole infections with kerion formation and treatment of tinea versicolor. 

Tolnaftate (1% cream, solution and gel) is indicated for treatment of tinea pedis (athlete s foot), t. cruris (jock itch), or t. corporis (ringworm) due to infection with Trichophyton rubrum, T. mentagrophytes, T. tonsurans, Microsporum canis, M. audouini, and Epidermophy ton floccosum, and as treatment for tinea versicolor due to Malassezia furfur. 

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