Tick-borne meningoencephalitis vaccine

Tick-borne meningoencephalitis vaccine is an adsorbed formalin-inactivated virus vaccine prepared on chicken embryo tissue. Mild local reactions (soreness, redness, swelling) have been reported in 10-25% of vaccinees systemic reactions occur at similar rates. Fever over 39° C is rare. 

The database of the Swiss Drug Monitoring Center included 20 spontaneous reports (1987 to July 1992) of adverse events after the administration of tick-borne meningoencephalitis vaccine, among them 11 reports of cases with neurological symptoms (for example menin-gism, polyradiculitis, ataxia, vestibulopathy, facialis paresis). Most recovered completely within a few days. The incompleteness of the data did not allow conclusions regarding the causality of immunization (3). 

A case of facial edema and pain and swelling of the left knee following the receipt of tick-borne meningoencephalitis vaccine was suspected to be caused by thiomer-sal allergy (7). 

Tick-borne meningoencephalitis vaccine [SEDA-15, 3423 SEDA-33, 663]... 

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