Thyroid cancer after injection

Figure 7. Gamma-camera views of a human subject with anaplastic thyroid cancer taken 24 h after intravenous injection of 25 nanomoles (2 mCi) of luln-BLEDTA. Arrows indicate metastases to the soft tissue of the face and lungs (18).

A considerable advance in the management of thyroid cancer has resulted from the introduction of recombinant human TSH (thyrogen). A dose of 0.9 mg is administered intramuscularly, followed by an identical dose 24 hours later. The serum thyroglobuLin is then measured 48-72 hours after the second TSH injection this has become the preferred diagnostic test for following patients with differentiated thyroid cancer who have had thyroidectomy and ablation of any remnant tissue with radioactive iodine. This regimen can also be used to stimulate iodine uptake by malignant cells in a total body scan (see below). 

In our small series, satisfactory results were obtained in 73.5% of the cases based on the reduction of opiate doses. One of the major advantages of the injection of alcohol into bone metastasis is the rapid relief of pain occurring within 24-48 h. Duration of pain relief ranged from 2-9 months. It should be pointed out that none of the patients survived beyond 9 months. In five cases, the alcoholization was not performed because of rich vascular opacification after contrast media injection (renal cell carcinoma and thyroid cancer). 

Soler et al. (2000) Gene therapy naked CMViNOS DNA Mouse orthotopic thyroid cancer (rMTC 6-23) Tumour size reduced by 50% after intra-tumoural injection... 

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