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Thymocyte proliferation assay

The multiple actions of individual cytokines mean that cell lines rarely respond only to one cytokine. This is well illustrated by the efforts to develop specific bioassays for lL-1. Although the original mouse thymocyte proliferation assay was thought to be IL-1 specific, it is now clear that many cytokines influence the assay. IL-6 and TNF can replace IL-1 (G7, U4), and IL-2 and IL-4 can sygerize with... [Pg.47]

Four polysaccharides (FCp-1, FCp-2, FCp-3 and FCp-4) were isolated from citrus fruits (Citrus medica L. var. sarcodactylis) after hot-water extraction and ethanol precipitation. Among all, only the FCp-3, a polysaccharide with a molecular weight of 177.1 KDa, showed an immunological activity evaluated by splenocyte and thymocyte proliferation assay. FCp-3 displayed a significant splenocyte proliferation at a dose of > 25 microg/mL, and showed a moderate effect on thymocyte proliferation at the same dose [70]. [Pg.12]

See other pages where Thymocyte proliferation assay is mentioned: [Pg.10]    [Pg.386]    [Pg.1131]    [Pg.220]    [Pg.530]    [Pg.242]    [Pg.419]   
See also in sourсe #XX -- [ Pg.4 ]



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