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Thymidine Kinase Substrates and Inhibitors

The Case Study Herpes Simplex Virus Type 1 Thymidine Kinase Substrates and Inhibitors [Pg.48]

C atoms in cyan, O in red, N in blue (N)-MCT C atoms in orange, O in red, N in blue) series. Hydrogen bonds are shown as dashed lines, (c) Correlation between kcat and the sugar-moiety-dipole-Glu225 electrostatic energy (electrostatic energetics). Interaction energy was [Pg.50]


Iqbal, J., Scapozza, L., Eolkers, G, and Muller CE., Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors. J. Chromatogr. B-Anal. Technol. Biomed. Life Sci., 846, 281-290, 2007. Wang, W, Tang, J., Wang, S., Zhou, L., and Hu, Z., Method development for the determination of coumarin compounds by capillary electrophoresis with indirect laser-induced fluorescence detection, J. Chromatogr. A, 2007. Vol 1148(1) 108-114. [Pg.47]




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