Thiols, arylation

Cuprous oxide, in thiol arylation, 50, 75 Curtius reaction, modiflcation using mixed carboxylic-carbonic aidiy-drides, 51, 51... 

Boots, A.W., Haenen, G.R., den Hartog, G.J., and Bast, A., Oxidative damage shifts from lipid peroxidation to thiol arylation by catechol-containing antioxidants, Biochim. Biophys. Acta, 1583, 279, 2002. 

Benzene thiol arylation with bromobenzene was reported by Foa et al. utilizing a biphasic aqueous-toluene system (Scheme 3.5) [12]. 

In 2009, Reddy et al. [150] reported the use of a nano-indium oxide as a recyclable catalyst for the ligand-free thiol arylation with both aryl bromides and iodides. The specific conditions were In Oj nanoparticles (3 mol%) and KOH (2 equiv) in DMSO for 24 h at 135 ° C. The scope was clearly demonstrated affording high yields of the product. The catalyst could be recovered by ultracentrifugation and reused up to four times without much loss in activity. 

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