Thermogravimetric analysis pharmaceutical applications

The book opens with the first three chapters devoted to differential scanning calorimetry (DSC), the most commonly used thermal method. These chapters cover the principles, optimal use, and pharmaceutical applications of the method. Subsequent chapters explore modulated temperature DSC, thermogravimetric analysis, thermal microscopy, microcalorimetry, high sensitivity DSC, dynamic mechanical analysis, and thermally stimulated current, all of which have attracted great interest within the pharmaceutical field. Each chapter includes theoretical background, measurement optimization, and pharmaceutical applications. 

Dedicates two chapters to the basic principles and pharmaceutical applications of thermogravimetric analysis... 

By definition, thermogravimetric analysis (TGA) is the measurement of the weight of a polymer sample as a function of temperature, time and/or atmosphere at a controlled temperature program. Usually, the evolution of the mass is measured in a high sensitive balance, under a well-defined atmosphere (inert or reactive gas) and plotted against temperature. TGA is used not only for polymeric materials, but also to characterize materials used in various environmental, food, pharmaceutical, and petrochemical applications. An example of a TGA plot is presented in Fig. 7.18. 

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