Therapeutic angiogenesis cell-based therapy

Losordo DW, Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease part II cell-based therapies. Circulation 2004 109 2692-2697. 

Molecular imaging has also been used to measure general processes such as angiogenesis, inflammation, hypoxia, or arteriosclerosis. As many diseases result in abnormalities of these processes (also named common denominators ), drug-based therapies aim at their modification. In other cases - such as the apoptosis of tumor cells - a change in this process is a desired therapeutic effect. For these reasons, quantitative measurement of the status of these processes may represent potential biomarkers of drug efficacy. 

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