Therapeutic agents benzoic acid

Amino-3-fluorobenzoic acid is an important intermediate in the synthesis of derivatives of indole, such as the potent and selective thromboxane/prostaglandin endoperoxide receptor antagonist L-670,5964 or the anti-inflammatory agent Etodolac.5 Compounds of this type have therapeutic applications. 2-Amino-3-fluoro-benzoic acid is also an important precursor for the synthesis of fluoroacridines, which can be converted to interesting tridentate ligands, such as Acriphos.6... [Pg.202]

Benzoic acid also has a long history of use as an antifungal agent in topical therapeutic preparations such as Whitfield s ointment (benzoic acid 6% and salicylic acid 3%). [Pg.66]

Combinatorial chemistry has proved of value in the development of therapeutic agents. A method for solid-state synthesis of an oxalic acid library involving conversion of anthranilic acid derivatives into 2-(oxalylamino)benzoic acids has been reported137. [Pg.777]

Disperse blue 35 Amino-benzoic-acid derivative Amyl-o-dimethylaminobenzoic acid Furocoumarins Therapeutic agents 8-Methoxypsoralen 4,5,8-T rimethylpsoralen 5-Methoxypsoralen (Bergapten)... [Pg.318]