Thelenota ananas

Frondoside B (9a), Cucumariosides A2-4 (9b) and A7-3 (9c), Fig. (9) as well as several triterpene glycosides isolated from the sea cucumbers Stichopus chloronotus (lOa-lOh) and Thelenota ananas (lOi, lOj), Fig. (10) contain the simple 3 (5-hydroxyholost-7-ene as the aglycone. An additional acetoxyl group in the side chain is present in compounds 10a-... 

Glycosides lOa-lOj were isolated from Stichopus chloronotus and Thelenota ananas, two sea cucumbers belonging to the order Aspidochirota [37]. 

Fig. (10). Structures of glycosides isolated from the sea cucumbers Stichopus chloronotus and Thelenota ananas...

Several triterpene glycosides isolated from the sea cucumbers Cucumaria frondosa, Cucumaria japonica, Stichopus chloronotus and Thelenota ananas contain the simple 3P-hydroxyholost-7-ene as the aglycone (49) [55]. Recently, three new monosulfated pentaglycosides, frondosides Ai-2 (49a) A2-3 (49b) and A2-4 (49c), Fig. (18) were isolated from the sea cucumber Cucumaria frondosa [61, 62]. 

Five non-sulfated triterpene glycosides, synallactosides Ai (52a), A2 (52b), Bi (52c), B2 (52d) and C (52e), Fig. (21) were isolated from the deep-water North Pacific sea cucumber Synallactes nozawai [73]. Synallactoside Ai is the 25,26-dehydro derivative of thelenotoside A, isolated from Thelenota ananas as a mixture with thelenotoside A [74]. Compounds 52b-52e are new compounds with interesting features in the carbohydrate chains of synallactosides A2, Bi, and B2. Synallactoside A2 (52b) is the first glycoside isolated from sea cucumbers with two terminal 3-(9-methylxylose residues in the oligosaccharide chain. On the other hand, the carbohydrate chains of synallactosides Bi (52c) and B2 (52d) have unprecedent structures among holothurins. 

Fucoidan composed of tetrafucose Thelenota ananas (sea cucumber) 127... 

Kelecom, a., B. Tursch, and M. Vanhaelen Chemical Studies of Marine Invertebrates XIX. Glycosidic Chain Structure of Thelothurins A and B, Two New Saponins from the Indo-Pacific Sea Cucumber Thelenota ananas Jaeger (Echinodermata). Bull. Soc. Chim. Belg. 85, 277 (1976). 

Stonik, V.A., I.I. Mal tsev, and G.B. Elyakov The Structure of Thelenotosides A and B from the Holothurian Thelenota ananas. Khim. Prir. Soedin. 1982, 624. 

Kelecom, A., Daloze, D., and Tursch, B. (1976a) Chemical studies of marine invertebrates. XXI. Six triterpene genin artifacts from thelothurins A and B, toxic saponins of the sea cucumber Thelenota ananas Jaeger (echinodermata) biosynthesis of the thelothurins. Tetrahedron, 32, 2353-2359. 

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