The role of T cells

Trautmann A, Akdis M, Brocket EB, Blaser K, Akdis CA New insights into the role of T cells in atopic dermatitis and allergic contact dermatitis. Trends Immunol 2001 22 530-532. 

The activation of mast cells and T cells results in late-phase reactions. Both immediate hypersensitivity and late-phase reactions are evident in the skin of atopic as well as nonatopic individuals after the cross-linking of IgE-bound mast cells with an antibody against IgE. The atopic asthmatic could develop late-phase reaction even in the absence of mast cell-related immediate hypersensitivity reaction, which is mast cell-independent and HLA-dependent, suggesting the role of T cells by themselves in causing asthma symptoms in atopic asthmatics. 

Sayegh MH, Turka LA. 1998. The role of T cell costimulatory activation pathways in transplant rejection. NEJM. 338 1813-1821. 

Although the role of T cells in RA has been the focus of intensive debate during the past decade, there is now unequivocal evidence that T cells and their products are active in this disease (128). 

The role of T-cells in the pathophysiology of COPD is not yet certain, although they have the potential to produce extensive damage in the lung. CD8" " cells have the capacity... 

Bagavant H, Fu SM (2005) New insights from murdne lupus dissociation of autoimmunity and end organ damage and the role of T cells. CuiT Opin Rlieumatol 5 523—528. 

Van dWJ, Shimoda S, Niho Y, Coppel R, Ansari A, Gershwin M. The role of T cells in primary biliary cirrhosis. Semin Liver Dis 1997 17 105-13. 

Gonzalo JA, Lloyd CM, Kremer L, Finger E, Martinez AC, Siegelman MH, Cybulsky M, Gutierrez-Ramos JC (1996) Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors. J Clin Invest 98 2332-2345... 

Cavani, A, De Pita, O. (2006 Feb). The role of T cells in drug reaction. Current Allergy and Asthma Reports, 5(1), 20-24. 

The controversy surrounding the role of T cells in the perpetuation of rheumatoid synovitis has been discussed previously. The effect of anti-T cell mAbs has been perceived as a test of the truth of T cell hypothesis. 

---