The Intersection of Ligandability and Human Disease Target Space

The Intersection of Ligandability and Human Disease Target Space 

Estimates of the extent of the human druggable genome vary widely [16-18]. For the purposes of most analyses, druggable targets are assumed to comprise 

Triangles metal ions or metalloenzymes solid triange , small anions drcle natural ligands solid circle enzyme inhibitors. (Reproduced with permission from National Academy of Sdences USA [15].) 

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