The Combined Effect of Temperature and Solvent Composition on Solute Retention

The Combined Effect of Temperature and Solvent Composition on Solute Retention 

If the relationship between retention volume and temperature is known, as well as its dependence on solvent composition, then the combined effect of both solvent 

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The effect of temperature, although significant, is not nearly as great as that from the ethanol content and is greatest at low concentrations of the polar solvent. It is clear, that the solute retention is the least at high ethanol concentrations and high temperatures, which would provide shorter analysis times providing the selectivity of the phase system was not impaired. The combined effect of temperature and solvent composition on selectivity, however, is more complicated and to some extent 

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