Thalomid - Thalidomide

Clark TE, Edom N, Larson J, Lindsey LJ. Thalomid (thalidomide) capsules a review of the first 18 months of spontaneous postmarketing adverse event surveillance, including off-label prescribing. Drug Saf 2001 24(2) 87-l 17. [Pg.716]

Cytadren - aminoglutethimide Megace - megestrol acetate Thalomid - Thalidomide... [Pg.395]

Figure 1.10 Thalomid (thalidomide), Revlimid (lenaiidomide), Vioxx (rofecoxib), Lamprene (clofazimine), and Seldane (terfenadine).

Thalidomide (Thalomid) Severe birth defects, peripheral neuropathy, deep vein thrombosis, somnolence, constipation Start at 50 mg by mouth daily and titrate to a maximum of 800 mg doses are taken nightly Women of childbearing age must use two forms of contraception Pregnancy test must be taken before and during use... [Pg.1422]

Thalidomide (Thalomid) Topotecan (Hycamtin) Tretinoin, Topical [Retinoic Acid] (Retin-A, Avita, Renova, Retin-A Micro)... [Pg.39]

Thalidomide (Thalomid) is a derivative of glutamic acid that is chemically related to glutethimide. It exerts a number of biological effects as an immunosuppressive, antiinflammatory, and antiangiogenic agent, yet its mechanisms of action have not been fuUy elucidated. Thalidomide potently inhibits production of tumor necrosis factor (TNF) a and interleukin (IL) 12, and its effect on these and other cytokines may account for some of its clinical effects. [Pg.490]

THALOMID (Celgene) (thalidomide) capsules February 2004 labeling... [Pg.256]

Thalidomide (Thalomid] Multiple myeloma Peripheral neuropathy dizziness drowsiness Gl distress (nausea, diarrhea, stomach pain] contraindicated in pregnant women because of teratogenic potential... [Pg.581]

Teniposide Vumon- Bristol-Myers Squibb Oncology) Thalidomide Thalomid-Celgene)... [Pg.400]

N-Phthalylglutamic acid imide N-(2,6-Dioxo-3-piperdyl)-phthalimide Talimol Sedalis Kevadon Distavil Thalomid NSC-66847 Chemical/Pharmaceutical/Other Class Thalidomide is a piperidinedione derivative Chemical Formula C13FI10N2O4 Chemical Structure ... [Pg.2554]

Tenoretic atenolol, chlorthalidone thalidomide Contergan, Distaval, Kevadon, Thalomid... [Pg.681]

Additional anti-TNF therapies are being evaluated in treating Crohn s disease, including a more humanized monoclonal antibody (CDP571) that should be less antigenic, and thalidomide (Thalomid), a drug with significant anti-TNF-a effects. [Pg.352]

Thalidomide (thalomid) is used to treat patients with relapsed and refractory MM, as well as early stage disease. The National Comprehensive Cancer Network (NCCN www.nccn.org) Clinical Practice Guidelines for Multiple Myeloma includes thalidomide as an option for salvage therapy in patients with relapsed or refractory MM, or as initial therapy in combination with dexamethasone for patients with advanced myeloma. Thalidomide is also in clinical trials for use in treating a variety of solid tumors and myelodysplasias. [Pg.897]

Thalidomide (thalomid) is best known for the severe birth defects it caused when administered to pregnant women. For this reason, it is available only under a restricted distribution program and can be prescribed only by specially licensed physicians who understand that thalidomide should never be taken by women who are pregnant or who could become pregnant while taking the drug. Nevertheless, it is indicated for the treatment of patients with erythema nodosum leprosum (see Chapter 47) and also is used in conditions such as multiple myeloma. Its mechanism of action is unclear. [Pg.920]

Thalidomide (thalomid) is an anti-inflammatory, immunomodulating, antiangiogenic agent see Figure 51-6) that also can increase keratinocyte migration and prohferation. [Pg.1089]

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