Tetraazaporphyrin, synthesis

Tetraaza macrocycles nickel complexes, 5, 5 synthesis, 2, 903 Tetraazaporphyrin, octaphenyl-metallation, 2, 858 Tetraazaporphyrins synthesis, 2, 857... 

Tetraazaporphyrin, octaphenyl-metallation, 858 Tetraazaporphyrins synthesis, 857 Tetraethylenepentamine metal complexes, 56 Tetraglycine metal complexes, 764 Tetraketones metal complexes, 399 1,3,5,7-Tetraketones metal complexes, 400 Tetramines cyclic... 

M. Ratajski, J. Osterloh, D. Gabel. Boron-containing chlorins and tetraazaporphyrins Synthesis and ceU uptake of boronated pyropheophorbide A derivatives. Anti-Cancer Agents Med. Chem., 2006, 6, 159-166. 

Ratajski, M. Osterloh, J. Gabel, D. Boron-Containing Chlorins and Tetraazaporphyrins Synthesis and Cell Uptake of Boronated Pyropheophorhide A Derivatives. Curr. Med. Chem., Anti-Cancer Agents 2006,... 

Porphyrazines (pz), or tetraazaporphyrins, are compounds that can be viewed as porphyrin variants in which the meso carbon atoms are replaced with nitrogen atoms, as Fig. 1 shows (1). This difference intrinsically gives porphyrazines discrete physiochemical properties from the porphyrins. In addition, despite their similar molecular architecture, porphyrazines are prepared by an entirely different synthetic route than porphyrins—by template cyclization of maleonitrile derivatives, as in Fig. 2, where the open circle with the A in it represents the peripheral substituent of the pz—rather than by the condensation of pyrrole and aldehyde derivatives (1). The pz synthetic route allows for the preparation of macrocycles with chemical and physical properties not readily accessible to porphyrins. In particular, procedures have been developed for the synthesis of porphyrazines with S, N, or O heteroatom peripheral functionalization of the macrocycle core (2-11). It is difficult to impossible to attach the equivalent heteroatoms to the periphery of porphyrins (12). In addition, the preparation and purification of porphyrazines that bear two different kinds of substituents is readily achievable through the directed cocyclization of two different dinitriles, Fig. 3 (4, 5, 13). 

The synthesis of it-conjugated photochromic Mg(II) tetraazaporphyrin appended with octakis(4-phenyl-buta-l,3-dienyl) hybrid (Scheme 13) began with the reaction of the magnesium powder with dry n-propanol under Ar. After the formation of... 

Synthesis and characterization of other related macrocycles, including chlorins, " isobacteriochlorins, bacteriochlorins, mono- and dioxoporphyrins, " other more highly saturated hydroporphyrins, N-alkyl- or A-arylporphyrins, some of which are chiral, porphodimethenes, thiaporphyrins, " oxaporphyrins, N-confused " and carbapor-phyrins, porphycenes " and corrphycenes, " tetraazaporphyrins, phthalocyanines, the ring-expanded sapphyrins, texaphyrins and others, and the ring-contracted corroles " and corrolazines have also been synthesized and are discussed in the indicated references. 

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