2- tert-Butyl-4-methoxyphenol

Table 3. Polymerization of methacrylic esters via enolatealuminum porphyrins 2 in the presence of methylaluminum bis(2-tert-butyl-4-methoxyphenolate) (3c) ...

Butylmercuric nitrate, AD22 2-tert-Butyl-4-methoxyphenol, AT95 2-(Butylmethylamino)ni trobenzene,... 

Although the corresponding 4-methyl and 4-phenyl analogues failed to similarly react, 2-tert-butyl-4-methoxyphenol in acetic acid containing copper(ll) acetate when refluxed for 24 hours under argon afforded a 70% yield of 2-acetoxy-4-methoxy-6-tert-butylphenol (ref. 174). 

AT95 CnHigOs 2-tert-butyl methoxyphenol 1XR BQ E01 2-H0-5-CH30C6H3 c(ch3)3 Hs0 V Y buffer 0 GE/CdSE 0-0 ... 

Butylated Hydroxyanisole. 2- and 3-/ -Butyl-4-methoxyphenol (butylated hydroxyanisole (BHA)) is prepared from 4-methoxyphenol and tert-butyl alcohol over silica or alumina at 150°C or from hydroquinone and tert-butyl alcohol or isobutene, using an acid catalyst and then methylating. It is widely used in all types of foods such as butter, lard, and other fats, meats, cereals, baked goods, candies, and beer as an antioxidant (see Antioxidants Food additives). Its antioxidant properties are not lost during cooking so that flour, fats, and other BHA-stabilized ingredients may be used to produce stabilized products. 

Problem 19.26 From readily available phenolic compounds, synthesize the anitoxidant food preservatives (a) bha (fert-butylatedhydroxyanisole, a mixture of 2- and 3-tert-butyl-4-methoxyphenol (b) BHT (tert-butylated hydro-xytoluene). ... 

C15H22 1 -(1,5-dimethyl-4-hexenyl)-4-methy benzene 644-30-4 565.39 50.201 2 28772 C15H2402 2,6-di-tert-butyl-4-methoxyphenol 489-01-0 523.15 46.113 2... 

Tribromo-m-cresol is oxidized by chromium trioxide in 70% acetic acid at 70-75 °C within 10 min to dibromo-m-toluquinone (3,5-dibromo-2-methyl-p-benzophenone) in 77% yield [559]. 2-BVomo-4-hy-droxy-5-methoxybenzyl alcohol treated with Fremy salt at pH 6 at room temperature for 1 h gives an 84% yield of 2-bromo-5-methoxy -benzo-quinone [487]. 4-Benzyl-2,6-dibromophenol, on oxidation with bromine in a sealed tube, yields 2,6-dibromophenylchinomethide [732] (equation 312). The oxidation of 2,5-di-tert-butyl-4-methoxyphenol with mercuric oxide or... 

BHA tert-butyl-4-methoxyphenol 1,1-dimethylethyl-4-meth-oxyphenol E320 Nipanox BHA Nipantiox 1-F Tenox BHA. 

The commercially available material can have a wide melting point range (47-57°G) owing to the presence of varying amounts of 3-tert-butyl-4-methoxyphenol. 

Phenols usually serve as radical inhibitors in conventional radical polymerization but can enhance the polymerizations of MMA with 1-21 (X = Br)/CuBr/ L-9 (R = n-Pen).231 For example, on addition of 10 equiv of 2,6-di-tert-butyl-4-methylphenol with respect to initiator ([1-21] [CuBr] [L-9] [phenol] = 1 3 1 10), the conversion increased from 55% to 75% in 4 h in xylene at 90 °C without any changes in the MWDs. Similar effects were observed for 4-methoxyphenol, phenol, and 2,6-di-ZerZ-butylphenol.231 233 No inhibition but enhancement of the polymerization by the addition of phenols may suggest that the growing species is different from that in conventional radical polymerization. However, phenols do not act as... 

Relative finh values to BHT = 1.82 x 10" M s determined under the same conditions taken from Reference 152. The stoichiometric factor, n, determined compared to 2,6-di-tert-butyl-4-methoxyphenol, equals 2. 

A new C-allyl cardano 1 derivative formed by Claisen rearrangement of an allyl ether namely, 2-allyl-3n-pentadecyl-6-tert-butylphenol had comparable antioxidant properties to the well known compounds DBHA and BHT, respectively 2,6-di-tert-butyl-4-methoxyphenol and 2,6-di-tert-butylphenol [252], The 2-allyl compound is related in properties to the precursor 2-tert-butyl-5n-pentadecylphenol (see, e.g. p. 542 in ref.[l] and [253] and to the hindered phenols [254],... 

Dimethylethyl)-4-methoxyphenol Anisole, butylated hydroxy- Antioxyne B Antrancine 12 BHA BOA (antioxidant) Butyl hydroxyanisole Butylated hydroxyanisole Butylhydroxyanisole 2-terc.Butyl-4-methoxyifenol 2(3)-t-Butyl-4-hydroxyanisole 3-t-Butyl-4-hydroxyanisole t-Butyl hydroxyanisole tert-Butyl-4-hydroxyanisole Butylohydroksyanizol CCRIS 102 EEC No, E320 EINECS 246-563-8 Embanox FEMA No. 2183 HSDB 3913 Nepantiox 1-F Nipantiox 1-F Phenol, 1,1-dimethylethyl)-4-methoxy- Phenol, tert-butyl-4-methoxy- Protex Sustane 1-F Tenox BHA. Mixture of isomers of t-butyl-substituted 4-methoxyphenols antioxidant and preservative for foods mp = 48-55 bp 33 = 264-270 insoluble in H2O, soluble in organic solvents LDm (rat orl) = 2200 mg/kg. Eastman Cham. Co. Mpa Penta Mfg. UOP. 

The dihydric phenols are speciality products widely used industrially and commercially. Hydroquinone and its relative, 4-methylaminophenol (metol) are the main chemicals used for development in black and white photography. Butylated hydroxyanisole, (BHA) mainly 2,6-di-tert-butyl-4-methoxyphenol (5), an important food antioxidant is synthesised from 2,4,6-tri-t-butylphenol by reaction in methanolic solution with chlorine to give 2,4,6-tri-t-butyl-4-methoxy-... 

The widely used antioxidant and food preservative called BHA (butylated hydroxyanisole) is actually a mixture of 2-iert-butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol. BHA is synthesized from p-methoxyphenol and 2-methylpropene. (a) Suggest how this is done, (b) Another widely used antioxidant is BHT (butylated hydroxy-toluene). BHT is actually 2,6-di-iert-butyl-4-methylphenol, and the raw materials used in its production are p-cresol and 2-methylpropene. What reaction is used here ... 

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