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Template assembled synthetic protein

Steiner V, Schar M, Bomsen KO, Mutter M (1991) Retention behaviour of a template-assembled synthetic protein and its amphiphilic building blocks on reversed-phase columns. J Chromatogr 586 43-50... [Pg.118]

Fig. 4. Schematic representation of template-assembled synthetic proteins. The conforma-tionally restricted template can be orthogonally protected and sequentially linked to helical segments to form a large variety of functionalized TASP proteins. Flexible spacers that connect the folded peptide segments and the template provide the necessary conformational freedom that will allow the hydrophobic residues to find their optimum orientations for packing the core... Fig. 4. Schematic representation of template-assembled synthetic proteins. The conforma-tionally restricted template can be orthogonally protected and sequentially linked to helical segments to form a large variety of functionalized TASP proteins. Flexible spacers that connect the folded peptide segments and the template provide the necessary conformational freedom that will allow the hydrophobic residues to find their optimum orientations for packing the core...
Mutter, M. and Vuileumier, S. (1989) A Chemical Approach to protein Design-Template-Assembled Synthetic Proteins (TASP). Angewandte Chemie, 28, 535-676. [Pg.309]

Fig. 15. The construction of artificial proteins by the TASP (template-assembled synthetic proteins) concept [31]. Peptidic structures are attached to a synthetic template to create artificial proteins with a defined three-dimensional architecture. (Reproduced with the permission of Ref. 1)... Fig. 15. The construction of artificial proteins by the TASP (template-assembled synthetic proteins) concept [31]. Peptidic structures are attached to a synthetic template to create artificial proteins with a defined three-dimensional architecture. (Reproduced with the permission of Ref. 1)...
Scheme 1 The Concept of Template-Assembled Synthetic Proteins (TASP) Topological Templates Induce Folding of Covalently Attached Peptide Blocks into Predetermined Packing Arrangements 5 13 141... Scheme 1 The Concept of Template-Assembled Synthetic Proteins (TASP) Topological Templates Induce Folding of Covalently Attached Peptide Blocks into Predetermined Packing Arrangements 5 13 141...
Parallel Four-Helix-Bundle Template-Assembled Synthetic Proteins via Thioester... [Pg.35]

Two-Domain Template-Assembled Synthetic Protein Molecules as Biosensors... [Pg.41]

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See also in sourсe #XX -- [ Pg.255 ]



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Protein template

Proteins assembling

Proteins synthetic

Synthetic assemblies

Template-assembled

Template-assembled synthetic protein conformation

Template-assembled synthetic proteins (TASPs

Template-assembled synthetic proteins TASP)

Templated assembly

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