Temperature gradient focusing

Balss et al. [26] reported enantiomeric resolution of glutamic acid, dansyl-DL-glutamic acid, and baclofen with chiral temperature gradient focusing in... 

Ross, D., Locasdo, L.E., Microfluidic temperature gradient focusing. Anal. Chem. 2002, 74(11), 2556-2564. 

Teflon AF amorphous Teflon or copolymer of PTFE and 2,2-bis(trifluoro-methy l)-4,5-difluoro-1,3-dioxide Teryl 2,4,6-trinitrophenyl-iV-methylnitramine TFA trifluoroacetic acid TGF temperature gradient focusing TGGE temperature gradient gel electrophoresis Ti titanium... 

Temperature gradient focusing focuses charged species by balancing an axially varying electrophoretic flux with a counterflow, causing species to focus at locations where their net fluxes sum to zero (Figure 38.10) [56]. 

Balss, K.M., et al., DNA hybridization assays using temperature gradient focusing and peptide nucleic acids. 7. Am. Chem. Soc., 2004,126 13474-13479. 

Huber, D.E. and Santiago, J.G., Taylor-Aris dispersion in temperature gradient focusing. Electrophoresis, 2007, 28 2333-2344. 

Kim, S.M., et al.. Low-power concentration and separation using temperature gradient focusing via Joule heating. Area/. Chem., 2006, 78 8028-8035. 

Huber, D.E., Transport and Dispersion in Microfluidic Temperature Gradient Focusing, Ph.D Thesis, 2006, Stanford University. 

Temperature gradient focusing (TGF) is a relatively new technique for the concentration and separation of ionic species in microchannels or capillaries (Figure 50.17). The first TGF on chip was reported by Ross and Locascio in 2002. In TGF, one end of the channel is heated while the other end is cooled, resulting in a temperature difference along the channel. 

Ross and Locascio" reported the first microfluidic device for temperature gradient focusing. They used the TrisA>orate buffer due to the non-constant/(T). Copper blocks were used at the ends of the microchannels to realize the temperature gradient. With this setup, a 10,000-fold increase in... 

Balss, K. M., Vreeland, W. N., Phinney, K. W, and Ross, D., Simultaneous concentration and separation of enantiomers with chiral temperature gradient focusing. Analytical Chemistry, 76, 7243-7249, 2004. 

Munson MS et al (2007) Temperature gradient focusing with field-amplified continuous sample injection for dual-stage analyte enrichment and separation. Anal Chem 79(16) 6201-6207... 

Shackman JG, Munson MS, Ross D (2007) Temperature gradient focusing for microchannel separations. Anal Bioanal Chem 387(1) 155-158... 

Temperature gradient focusing was first reported by Ross and Locascio [1]. In principle, with... 

Temperature Gradient Focusing, Fig. 1 Schematic illustration of temperature gradient focusing in a microchannel. The microchannel is heated at one end and cooled at the other, producing a temperature gradient in the middle. The sample solute velocity Mt is the summation of two opposite velocities the electrophoretic... 

Temperature Gradient Focusing, Fig. 3 Temperature variation along the centerline of the microchannel... 

Temperature Gradient Focusing, Tabie 1 Expressions for the temperature-dependent functions of the solute mass diffusivity (fi)(T)), solute electrophoretic mobility (fep(T)), and buffer electrical conductivity (fu-iX) and fx-(T)) ... 

Temperature Gradient Focusing, Fig. 5 Sample solute concentration crmtonrs near the junction of the narrow and... 

---