Target organ toxicity skin sensitization

Health hazards Acute toxicity, skin irritation/cor-rosion, eye irritation/corrosion, respiratory or skin sensitization, mutagenicity, carcinogenicity, toxic to reproduction, target organ toxicity. 

F roperties Colorless liq., pleasant lemon-like odor sol. in alcohol, ether prad. insol. in water m.w. 1%.23 dens. 0.847 (15.5/15.5 C) vapor pressure 20 mm Hg (68 C) m.p. -96.9 C b.p. 175-176 C (763 mm) flash pt. (CC) 45 C autoignition temp. 237 C ref. index 1.4744 dielec, const. 2.3 Toxicology LD50 (oral, rat) 5000 mg/kg skin irritant and sensitizer inh. of vapor may cause nose and throat irritation probable eye irritant not very toxic by ing. target organs CNS, skin, kidney TSCA listed Environmental VOC ThOD 3.29... 

BHA is harmful if swallowed, inhaled, or absorbed through skin. It is irritating to the eyes, skin, mucous membranes, and upper respiratory tract. Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. The target organs for toxicity are liver, lungs, and forestomach. 

Chemical mixtures in cosmetics give rise to enhanced toxicity, low level toxicity, and unexpected target organ attack. Cosmetic products are composed of many lipophilic and hydrophilic chemicals. Numerous instances of strange injuries, including chemical burns and skin and respiratory sensitization from the use of cosmetic products, have been documented in which the injuries sustained could not be accounted for by a consideration of the individual chemicals involved J3°l... 

Toxicology LD50 (oral, rat) 650 pl/kg highly toxic readily absorbed thru skin sensitizer target organs liver, kidneys TSCA listed Precaution Corrosive... 

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