Tardive dysmentia

Myslobodsky, M. S. 1993, Central determinants of attention and mood disorder in tardive dyskinesia ( tardive dysmentia ), Brain Cogn., vol. 23, no. 1,... 

A clinical study of hospitalized drug-treated patients found many suffering from mental deterioration typical of a chronic organic brain syndrome that the researchers labeled dysmentia (Wilson et ah, 1983). Tardive dysmentia consists of unstable mood, loud speech, and [inappropriately close] approach to the examiner. It is probably a variant of hypomanic dementia.1 The mental abnormalities in the study by Wilson et al. (1983) correlated positively with TD symptoms measured on the Abnormal Involuntary Movement Scale. In addition, length of neuroleptic treatment correlated with three measures of dementia unstable mood, loud speech, and euphoria. The authors stated, It is our hypothesis that certain of the behavioral changes observed in schizophrenic patients over time represent a behavioral equivalent of tardive dyskinesia, which we will call tardive dysmentia (p. 188). The tendency in the literature, perhaps in search of a euphemism, has been to use the term tardive dysmentia even when a full-blown dementing syndrome is described. 

Chapter 3 documented that the neuroleptics can produce acute depression and psychosis. This chapter has documented the existence of tardive dysmentia and tardive dementia as well as tardive behavioral abnormalities in children. There is further evidence that the neuroleptics can... 

Goldberg, E. (1985). Akinesia, tardive dysmentia, and frontal lobe disorder in schizophrenia. Schizophrenia Bulletin, 11, 255-263. 

Jones, B. D. (1985). Tardive dysmentia Further comments. With commentary by S. Muk-herjee and R. M. Bilder. Schizophrenia Bulletin, 11, 87-190. 

Mukherjee, S. (1984). Tardive dysmentia A reappraisal. Schizophrenia Bulletin, 10, 151-152. 

Myslobodsky, M. (1986). Anosognosia in tardive dyskinesia Tardive dysmentia or tardive dementia Schizophrenia Bulletin, 12, 1-6. 

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