Taenia saginata oncosphere antigen

Bonay, P., Gonzalez, L.M., Benitez, L., Foster, M., Harrison, L.J., Parkhouse, R.M. and Garate, T. (2002) Genomic and functional characterisation of a secreted antigen of Taenia saginata oncospheres. Molecular and Biochemical Parasitology 121, 269-273. 

Gauci, C.G., Flisser, A. and Lightowlers, M.W. (1998) A Taenia solium oncosphere protein homologous to host-protective Taenia ovis and Taenia saginata 18 kDa antigens. International Journal for Parasitology 28, 757-760. 

Lightowlers, M.W., Rolfe, R. and Gauci, C.G. (1996b) Taenia saginata vaccination against cysticercosis in cattle with recombinant oncosphere antigens. Experimental Parasitology 84, 330-338. 

The following species of Taenia have been grown from oncospheres to active larvae with suckers T. hydatigena, T. ovis, T. pisiformis, T. serialis and E. granulosus (308, 314). The techniques of Heath Smyth (314), or modifications of them, have been used widely by other workers for the production and collection of E/S antigens of oncospheres in the preparation of potential vaccines (see Chapter 11, p. 302). Only limited success has been achieved with the culture of larval T. saginata (310, 471) and almost none with T. solium, and the in vitro culture of these important species remains a challenge. 

---