Tabernaemontana dichotoma

Related alkaloids 19,20-Z-vallesamine (10a) and 19,20-E-vallesamine (10b) have been extracted from the leaves of Alstonia scholaris (87H(26)413), from the bark of Tabernaemontana dichotoma (85P2097) and from cell cultures Tabernaemontana divaricata (88MI393). [Pg.83]

Tabernaemontana dichotoma (L.) R. Br. ex Roem et Schult. (syn Ervatamia coronaria, E. divaricata, Tabernaemontana coronaria, Rejoua dichotoma) [Apocynaceae]... [Pg.13]

All the alkaloids belonging to this group in Sri Lankan plants have been isolated by Perera, Sandberg, Verpoorte, and co-workers from various parts of Tabernaemontana dichotoma of the family Apocynaceae. Apparicine... [Pg.50]

Three alkaloids of this group, voaphylline (135), 12-methoxyvoaphyl-line (136), and voaphylline hydroxyindolenine (137), were isolated from Tabernaemontana dichotoma. Seeds of this plant afforded voaphylline (135) and voaphylline hydroxyindolenine (137) (89), whereas the fruits and leaves yielded 12-methoxyvoaphylIine (136) and voaphylline hydroxyindolenine (137) (91,92). [Pg.57]

Dichomine (161) is a novel type of iboga alkaloid reported in 1983 by Perera, van Beek, and Verpoorte from the leaves of Tabernaemontana dichotoma (100). It was later found to occur in the fruits of the same species (91). Dichomine, Q9H24N2O, showed an unusual UV spectrum with... [Pg.65]

Isomethuenine (166) is a minor tertiary indole alkaloid occurring in Tabernaemontana dichotoma leaves (92), fruits, and stem bark (93). [Pg.70]

Tubotaiwine (168), a condylocarpine-type indole alkaloid, obtained from Tabernaemontana dichotoma of Sri Lankan origin, was subjected to a stereochemical investigation with extensive NMR studies involving NOE dif-... [Pg.71]

In an extensive study of indole alkaloids from Tabernaemontana dichotoma, Perera and co-workers reported the isolation and characterization of eight bisindole alkaloids of the vobasine-coronaridine type (90,93). Of these, the previously known alkaloids tabernamine (173), voacamine (175), and 3 R/S-hydroxyvoacamine (178) were identified from their spectral characteristics and co-TLC with authentic samples (91). UV, IR, and XH NMR data of three of the bisindole alkaloids indicated a close structural relationship to tabernamine (173), and the XH NMR of one of these alkaloids was identical to that of tabernamine, except that the signal at 6 2.62 ppm due to the N-Me group was missing. The MS and IR spectroscopic data... [Pg.73]

Monogagaine (181), C39H44N4O2, is a new, minor bisindole alkaloid independently isolated from Sri Lankan Tabernaemontana dichotoma and T. chippii collected in the Ivory Coast (104). Structure elucidation of mono-... [Pg.74]

The most comprehensive study of a Sri Lankan medicinal plant was that of Tabernaemontana dichotoma conducted by Perera and co-workers (89,126). A preliminary pharmacological assay of the crude aqueous... [Pg.85]

Tabernaemontana dichotoma Tabemaemontana dichotoma Pleiospermium alatum Neonauclea zeylanica... [Pg.404]

Stem Tabernaemontana dichotoma Roxb. D. cingulatus Sth larval instars Topical +++ 119... [Pg.394]

Perera PK 1985 Phytochemical and pharmacological studies on Tabernaemontana dichotoma. Acta Pharm Suecica 22 64... [Pg.1151]

The fruit of the Ceylonese tree Tabernaemontana dichotoma) that has powerful narcotic seeds. [Pg.484]

The extracts of T. affinis, T. arborea, T. divaricata, T. heyrteana, and T. pandacaqui showed some degree of antitumor activity, whereas the extracts of T. malaccensis, T. dichotoma, and T. crassa exhibited hypotensive effects (9). Recently a systematic antimicrobial, antiamoebic, and antiviral screening of 19 different Tabernaemontana species has been carried out with positive results (218). [Pg.131]

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