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Synthetic hydrophobic degradable polymers poly

Poly(ortho esters) were first developed by the ALZA corporation (Alzamer) in 1970 in order to seek new synthetic polymer for drug delivery applications. These polymers degrade by surface erosion and degradation rates may be controlled by incorporation of acidic or basic excipients. The polymer is hydrophobic enough such that its erosion in aqueous environments is very slow. The unique features of poly(ortho esters), in addition to their surface erosion mechanism, is the rate of degradation for these polymers, pH sensitivity, and glass transition temperatures, which... [Pg.363]

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Degradable polymers

Degradeable polymers

Degraded poly

Hydrophobic poly ,

Hydrophobized polymers

Poly polymers

Polymer Synthetic polymers

Polymer degradation

Polymers hydrophobic

Synthetic degradable polymers

Synthetic hydrophobic degradable polymers

Synthetic polymers

Synthetic polymers degradation

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