Synthesis of hydrazones

Gadhwal, S., Baruah, M. and Sandhu, J.S., Microwave induced synthesis of hydrazones and Wolff-Kishner reduction of carbonyl compounds, Synlett, 1999, 1573-1574. 

Scheme 4 Synthesis of hydrazone linkages from hydrazide and aldehyde compounds...

With benzylic halides, the elimination requires sodium hydride in hot DMF, whereas aliphatic substrates do not undergo elimination at all. This drawback was surmounted by the use of N-4-acetoxyphe-iiyltrifiamide. 3 Elimination now occurs via the quinoneimines under mild conditions, even with aliphatic substrates (Scheme 17). Despite the ingenious chemistry, there appear to be few advantages over other methods. A procedure exists for the synthesis of hydrazones from halides (Scheme 18). ... 

JAPP KLINGEMANN Hydrazone Synthesis Synthesis of hydrazones from diazonium salts and an activated methylene group (or enamlne)... 

Scheme 59 Synthesis of hydrazones of hydrazido benzisothiazole derivatives...

Nun P, Martin G, Martinez J, Lamaty F. Solvent-free synthesis of hydrazones and their subsequent Af-alkylation in a ball-mill. Tetrahedron 2011 67 8187-94. 

Phenyl tetralone tosylhydrazone, 0.5% MEK (synthesis of hydrazones) (Curley et al. 1986)... 

Khan SA, Mullick P, Pandit S, Kaushik D (2009) Synthesis of hydrazones derivatives of quinoxalonine-prospective antimicrobial and anti-inflammatory agents. Acta Pol Pharm Dmg... 

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