Synthesis and Turnover of Macromolecules

The amount of material (e.g., macromolecule or metabolite) metabolized or processed per unit time. 2. The balance between synthesis and degradation of a biomolecule. 3. One complete turn of a reaction cycle. See Turnover Number Protein Turnover Pulse-Chase Experiments Exponential Decay... 

In primary cultures, articular chondrocytes grown in an artificial matrix after digestion of the original one, maintain their characteristic synthesis and turnover rate of cartilage matrix macromolecules... 

Energy for maintenance is the energy required for survival, or non-growth related purposes. It includes activities such as active transport across membranes and turnover (replacement synthesis) of macromolecules. 

The importance of the plasma membrane as the site of action of im-munologically mediated cytotoxicity reactions involving humoral or cellular factors has recently become evident. In this regard, several studies have shown that humoral immune killing reactions involve a complex series of biochemical interactions between the attacker moieties and the cell surface membrane.One approach in studying and elucidating such interactions could therefore focus on the effects of the immune attack processes on the synthesis and/or turnover of cell surface macromolecules known to be structural and functional components of the plasma membrane (e.g., proteins and lipids). 

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