Symyx

Product Summaries Symyx Software includes the following  

Software was developed with vendor neutral architecture. The software is 

Symyx Library Studio software provides an environment for the specification of one, several, or hundreds of experiments. Chemicals, mixtures, and process parameters are defined and then combined in a recipe-style user interface. 

The resulting experimental designs are saved to the Renaissance Application Server (RAS), where they provide a record of the compositional makeup of each sample in the design. The designs also provide the process conditions under which the sample was created for assessing composition/property relationships. 

The Library Studio Developer s Kit further extends Library Studio by embedding Microsoft s Visual Basic for Applications (VBA) into the Library Studio application. With VBA, the user can import data from statistical packages, such as DOE, or export data for further manipulation, such as a bubble point calculation. Additionally, modifications to the Library Studio user interface are possible via custom add-ins, such as commands to produce automated designs or validate a design intended for a particular instrument. 

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This initial medicinal chemistry ELN was followed into the market by products such as the Arthur suite from Synthematix and the iELN system from Intellichem (both since acquired by Symyx), which were more oriented at reaction planning and process chemistry. The heavyweight of the traditional cheminformatics companies, Elsevier MDL, also released a system, called Elan, which combined a Word-based front end with their well-known ISIS chemical technology on the back end (Fig. 9.3). 

Figure 11.17 Fluid reactant distribution in a microstructured reactor by a binary tree channel network. (From Berg, S.H. and Guan, S., W000/51720 to Symyx Technologies, Inc., March 1999.)...

The authors thank the Alexander von Humboldt-Stiftung (fellowships for T. Weskamp and V. P. W. Bohm) and the Fonds der Chemischen Industrie (studentships for T. Weskamp and V. P. W. Bohm). Special thanks goes to U. Tracht (Symyx Technologies) and to our pioneer in NHC chemistry, K. Ofele, for helpful discussions. 

THOMAS WESKAMP (1), Symyx Technologies, Santa Clara, California 95051... 

Fig. 4 Illustration of (a) Chemspeed automated synthesizer and (b) Symyx batch polymerization system for synthesis of discrete polymer libraries. Reprinted with permission from [90], (Copyright 2007 Taylor Francis Group, http //www.informaworld.com)...

MDL Available Chemicals Directory database 2007, Symyx Technologies, Inc., Santa Clara, CA 95051, USA. 

Many commercial vendors and academic labs provide collection of compounds or fragments (Sigma-Aldrige, Available Chemicals Directory (ACD) (http //www.symyx.com), Maybridge (www.maybridge.com), TCI America (http //www. tciamerica.com), ChemDB (51) (http //cdb.ics.uci.edu), ZINC... 

ISIS host from Symyx http //www.symyx. com/products/software / cheminformatics / isis-host/index.jsp... 

There exist a multitude of chemical reagent sources. The Available Chemical Directory (ACD) collection, from Symyx Technologies Inc., lists as many as 1,160,000 unique chemicals with chemical structure, pricing, supplier, purity, forms, etc. 

Symyx entered this competition in 1997 in collaboration with Hoechst with the goal of creating and validating primary and secondary synthesis and screening technologies and the use of this workflow to broadly explore mixed metal oxide compositions so as to discover and optimize new hits . The initial goal was a 10-fold increase in the space-time yield relative to the state-of-the-art MoVNb system for the ethane oxidative dehydrogenation reaction to ethylene. 

Fig. 1.3 HT-R. D workflow used in the oxidative dehydrogenation of the ethane program at Symyx Technologies.

Fig. 1.4 Comparison of STY with the composition as measured by Thorsteinson et al. [3] using traditional methods and by Symyx scientists using wafer-based...

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