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Switchable surfaces conformational changes

On the other hand, cells and proteins exhibit space- and time-dependent dynamic changes in their conformations and functionalities in the human body. Since the 1990s, dynamic switchable surfaces have been comprehensively studied in order to control the biomolecular dynamics by modification with smart polymers [6], which show changes in their conformations and properties in response to external stimuli. Among them, thermo-responsive poly(AT-isopropylacrylamide) (PNlPA/ m) is one of the most successful models to control the interaction between biomolecules and the grafted substrates by temperature... [Pg.279]

Another typical photoresponsive material for preparation of switchable surfaces is the spiropyran-merocyanine system. The spiropyran isomerizes to zwitterionic merocyanine conformation by UV exposure, and the reverse reaction can be triggered by irradiation with visible light as well as azobenzene. The changes in hydrophilic/hydrophobic properties through the isomerization of spiropyran groups also enable the control of cell adhesion/ detachment. Edahiro et al. reported photoresponsive cell culture substrates grafted... [Pg.287]

See other pages where Switchable surfaces conformational changes is mentioned: [Pg.231]    [Pg.43]    [Pg.500]    [Pg.43]    [Pg.113]    [Pg.500]    [Pg.280]    [Pg.285]    [Pg.286]    [Pg.289]    [Pg.290]    [Pg.173]    [Pg.139]    [Pg.140]    [Pg.329]    [Pg.173]    [Pg.467]    [Pg.600]    [Pg.52]    [Pg.401]    [Pg.153]    [Pg.176]    [Pg.391]   
See also in sourсe #XX -- [ Pg.282 ]



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Conformation change

Conformational changes

Surface change

Surface conformation

Switchability

Switchable surfaces

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