Surface iron oxide nanopartides

Gupta Ajay Kumar and Mona Gupta. (2005). Synthesis and surface engineering of iron oxide nanopartides for biomedical applications. Biomaterials, Volume 26, Issue 18, pp 3995-4021. 

One of the most important aspects of nanoparticles in biomedical applications is their surface functionalization in order to improve their biocompatibility with biological entities, and Fourier infrared spectroscopy (FTIR) is very useful technique that provides information about iron oxides in their ground electronic state, and when this material is bonding with a polymeric coating provides information about mechanism of functionalized magnetic nanopartides. This technique is widely used in characterization nanopartides due to its simplicity and availability. In magnetite structure it provides information about the excitation of vibration or rotation of the trivalent and divalent iron cations and allows knowing the occupied sites when the divalent iron is replaced with other cations. 

---