Supramolecular Polymers Containing Cyclodextrin

Construction of supramolecular structures using specific intermolecular interactions is one of the most important procedures for the construction of nano-scale architectures by bottom-up procedures. Recently, with the advent of host-guest chemistry and chemistry of molecular recognition, supramolecular science has made its appearance. 

Recently, much attention has been focused on the design and synthesis of intrerlocked molecules, such as rotaxanes and catenanes, because of their unique structures and properties.Host-guest interactions are used for the efficient preparation of such interlocked molecules. Previously, we found and reported that 

---

Summary The analysis of supramolecular structures containing polymers, and the discussion about the effect of polymeric materials with different chemical structures that form inclusion complexes is extensively studied. The effect of the inclusion complexes at the air-water interface is discussed in terms on the nature of the interaction. The entropic or enthalpic nature of the interaction is analyzed. The description of these inclusion complexes with different cyclodextrines with several polymers is an interesting way to understand some non-covalent interaction in these systems. The discussion about the generation and effect of supramolecular structures on molecular assembly and auto-organization processes is also presented in a single form. The use of block copolymers and dendronized polymers at interfaces is a new aspect to be taken into account from both basic and technological interest. The effect of the chemical structure on the self-assembled systems is discussed. 

When supramolecular polymers are treated with bulky stopper groups, they may form poly[2]rotaxane daisy chains [32,60-68]. Cyclic tri[2]rotaxanes (daisy chain necklace) containing cyclodextrins have been prepared from the mixture of 6-(4-aminocinnamoyl)-Q -CD and 2,4,6-trinitrobenzene sulfonic acid sodium salt [50,59] in an agueous solution (Fig. 21). If the molecule changes its conformation (or co-conformation), the ring may expand or shrink by external conditions (temperature, solvents, photochemically, elec-trochemically). These compounds are important because the cycle can be used as a chemical valve as seen in ion channels in biological membranes. 

Several examples of supramolecular assemblies involving synthetic macromolecules have been described as MRI contrast agents. An important approach is to exploit hydrophobic interactions between the cavity of cyclodextrins (CDs), mainly /S-CDs, and suitably functionalized Gd " " complexes. It has been recognized early on that the application of ohgomers or polymers of CDs containing several CD units represents further advantages with respect to... 

---