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Suprachiasmatic nucleus secretion

Figure 22.3 Possible links in the induction of circadian rhythm between daylight, the suprachiasmatic nucleus and melatonin release from the pineal gland. Some fibres in the optic nerve, projecting from the eye to the lateral geniculate nucleus (LGN) in the thalamus, innervate the suprachiasmatic nucleus (SCN) in the anterior hypothalamus, via the retinohypothalamic tract (RHT). Others project to the SCN from the LGN in the geniculohypothalamic tract (GHT). The release of melatonin into the circulation from the pineal gland (PG) is maximal at night and appears to be controlled partly by noradrenaline released from sympathetic nerves originating in the superior cervical ganglion (SCG). Melatonin receptors are found in the SCN, the removal of which dampens melatonin secretion... Figure 22.3 Possible links in the induction of circadian rhythm between daylight, the suprachiasmatic nucleus and melatonin release from the pineal gland. Some fibres in the optic nerve, projecting from the eye to the lateral geniculate nucleus (LGN) in the thalamus, innervate the suprachiasmatic nucleus (SCN) in the anterior hypothalamus, via the retinohypothalamic tract (RHT). Others project to the SCN from the LGN in the geniculohypothalamic tract (GHT). The release of melatonin into the circulation from the pineal gland (PG) is maximal at night and appears to be controlled partly by noradrenaline released from sympathetic nerves originating in the superior cervical ganglion (SCG). Melatonin receptors are found in the SCN, the removal of which dampens melatonin secretion...
Fig. 7.5 Interrelations between functional structures of the brain and their transmitter and hormone systems which are involved in the control of cortisol secretion (HPA axis, left part) and sleep patterns (right part). Abbreviations of the diverse nuclei SCN = suprachiasmatic nucleus, PVN = paraventricular nucleus, LC = locus coeruleus, DRN = dorsal raphe nuclei, LDT = laterodorsal... Fig. 7.5 Interrelations between functional structures of the brain and their transmitter and hormone systems which are involved in the control of cortisol secretion (HPA axis, left part) and sleep patterns (right part). Abbreviations of the diverse nuclei SCN = suprachiasmatic nucleus, PVN = paraventricular nucleus, LC = locus coeruleus, DRN = dorsal raphe nuclei, LDT = laterodorsal...
Mai LM, Pan J-T (1995) Bombesin acts in the suprachiasmatic nucleus to affect circadian changes in tuberoinfundibular dopaminergic neuron activity and prolactin secretion. Endocrinology 755 4136-4167. [Pg.512]

It Is synthesized in the pineal gland, and its secretion is controlled by the suprachiasmatic nucleus, following an endogenous ciroadian rhythm. Studies indicate that melatonin may ... [Pg.740]

The mammalian suprachiasmatic nuclei contain an endogenous pacemaker that generates daily rhythms in behaviour and secretion of hormones. They stimulate evening ACTH secretion in the rat (Cascio etal. 1987). Kalsbeek etal. (1996) used microdialysis-mediated intracerebral administration of the vasopressin V,-receptor antagonist to study the mechanisms underlying the circadian control of basic corticosterone release in the rat. By timed administration of the vasopressin antagonist divided equally over the day/night cycle, they were able to uncover the existence of an additional stimulatory input from the suprachiasmatic nucleus to the hypothalamo-pituitary-adrenal axis. [Pg.525]


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Suprachiasmatic nucleus

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