Supercritical fluid technologies mass transfer

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Lim, G. B., G. D. Holder, and Y. T. Shah. 1989. Solid-Fluid Mass Transfer in a Packed Bed under Supercritical Conditions. In Supercritical Eluid Science and Technology, 379-395. American Chemical Society. 

Supercritical Fluid Chromatography (SFQ and Supercritical Fluid Extraction (SFE) A separation technology similar to other extraction and chromatographic methods, but in which the mobile phase is actually a fluid in its supercritical fluid state. A supercritical fluid is a fluid that is held above its critical temperature and pressure, and for which no application of additioncJ pressure can result in the development of a liquid phase. Supercritical fluids are unique in that while they possess liquid-like densities, the mass transfer behavior is superior to that of liquids. Supercritical fluid chromatography remains a niche method that is applicable to pharmaceuticals and other high relative molecular mass solutes. Supercritical extraction, on the other hand, is more widely used as a sample preparation method, especially in pharmaceutical analyses, polymers, and environmental analyses. 

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