Sulfone synthesis

Postpolycondensation. See Solid-state postpolycondensation Potassium carbonate process, poly(arylene ether sulfone) synthesis via, 339 Pot life, 232 Powder coatings, 240 PPE. See Personal protective equipment (PPE)... 

Smith, Jason A., 431 Sn2+ compounds, 233 Sn4+ compounds, 232 SNAr reaction. See also Nucleophilic aromatic substitution reaction poly(arylene ether sulfone) synthesis via, 336-340... 

The usual sulfone synthesis by displacement of halide by sulfmate is assumed to have a nucleophilic 8 2 mechanism However, in special cases of alkyl halides with additional, electron-withdrawing substituents a radical substitution pathway has been observed (equation 32). Correspondingly, substitutions under formation of sulfones take... 

The mild conditions of the base-catalyzed sulfonate synthesis are particularly apparent in the case of two reactions in which the reacting OH groups are present in an azetidinone system 155... 

Cyanoamido-thiocarbamates, from cyan-amide and isothiocyanates, 297 Cyanohydrin, benzene sulfonates, synthesis of, from sodium cyanide and haJo-benzaldehyde, 297... 

Hyatt, J. A. Neber rearrangement of amidoxime sulfonates. Synthesis of 2-amino-1-azirines. J. Org. Chem. 1981,46, 3953-3955. 

Hinsberg sulfone synthesis. Formation of sulfonylquinol derivatives by addition of quinones to cold, dilute aqueous solutions of sulfinic acids. 

Wnuk, S.F., and Robins, M.J., Stannyl radical-mediated cleavage of Jt-deficient heterocyclic sulfones. Synthesis of a-fluoro esters and first homonucleoside a-fluoromethylene phosphonate, J. Am. Chem. Soc., 118, 2519, 1996. 

Shen, Y, Wang, G., and Sun, J., A novel stereoselective route to trifluoromethylated vinyl sulfones. Synthesis, 389, 2001. 

Anhydrous lanthanon nitrates, synthesis 11 Cyanogen, synthesis 12 Allophanyl hydrazide, synthesis 13 Urazole, synthesis 14 Organosilazane compounds, synthesis 16 IV-Nitrosohydroxyla-mine-iV-sulfonates, synthesis 31 Hydroxylamine-O-sul-fonic acid, synthesis 32... 

Sulfone synthesis. The salt (1) reacts with alkyl halides in THF at 20-40° (2-4 hr.) to give alkyl 4-methylphenyl sulfones, usually in yields of 60-90%. The analogous reaction with sodium p-toluenesulfinate itself proceeds in much lower yields, mainly because 0-alkylation competes with S-alkylation. ... 

Bera, S., Langley, G.J. and Pathak, T. (1998) Sugar-modified uridine bisvinyl sulfone synthesis of a bifunctionahzed nucleoside Michael acceptor and its use in stereoselective tandem cyclization. The Journal of Organic Chemistry, 63, 1754—1760. 

Sulfinate anions have been used as nucleophiles in palladium-catalyzed allylic alkylation [143]. More recently, both Cu- and Pd-catalyzed couplings of sulfinate anions with aryl halides have also been reported as a means to generate unsymmetrical diaryl sulfones, which are common motifs in bioactive molecules [38, 93, 144—148]. Similarly, Cu-catalyzed coupling of arylboronic acids with sulfinate anions has been reported [95,149,150]. Notably, Kantam and co-workers found that the use of ionic liquids permits Cu(OAc)2-catalyzed sulfone synthesis at ambient temperature and with convenient product separation and catalyst recyclability (17) [150]. 

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