Suggested Document Distribution Matrix

It is important to realize that a HAZOP or What-If safety review is not actually complete until all recommendations have been resolved and a close-out Addendum report is produced. 

All recommendations should be decided upon in a sound, rational, technical manner when all alternatives have been identified and studied. If such documentation is not prepared, future possible accident investigations may query legal implications. 

The Project Manager should be responsible for handling and resolving recommendations. He may designate a person to handle the day to day activities for this function. Typically a risk engineering or loss prevention engineer is nominated for this task. 

Once the project manager has a suggested course of action for each recommendation, these should be submitted to the appropriate higher level management for their concurrence. 

There are several possible actions for each recommendation when listed in the addendum report  

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A document distribution matrix is typically employed in project designs that indicate what documentation is to be provided to the company s personnel for review. A suggested document distribution matrix is provided in Table 14. This distribution matrix may supplement the facility or project drawing distribution matrix. 

Cell fractionation studies of five strains of cyanobacteria indicate that MAAs are located primarily (>90%) within the cytoplasm and not the cell sheaths, walls, or membranes.132 Extracellular placement of MAAs does occur in some cyanobacterial species that posses cellular sheath layers.134135 Extracellular MAAs are covalently bonded to oligosaccharide molecules embedded in the cyanobacterial sheath matrix and provide substantial protection to prevent photobleaching of chlorophyll within the cell. Intracellular or extracellular distributions of MAAs in eukaryotic cells have not been investigated. Based on the high MAA concentrations of Phaeocystis antarctica colonies, it has been suggested that MAAs are associated with the extracellular mucopolysaccharide matrix of the colony.125 This may be a more common phenomenon than currently recognized, and future research efforts will be necessary to further document extracellular occurrence of MAAs in cyanobacteria and algae. 

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