Subject a-selectivity

This chapter is in no way meant to impart a thorough understanding of the theoretical principles on which computational techniques are based. There are many texts available on these subjects, a selection of which are listed in the bibliography. This book assumes that the reader is a chemist and has already taken introductory courses outlining these fundamental principles. This chapter presents the notation and terminology that will be used in the rest of the book. It will also serve as a reminder of a few key points of the theory upon which computation chemistry is based. 

More information about GMP for pharmaceutical products can be obtained from specific guidelines and from books about this subject. A selection of these is listed in the Annex B to the registration requirement chapter. 

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