Studies of Tablets and Excipients

It is of interest to the pharmaceutical industry to be able to characterize drugs directly in their final dosage forms. Two of the first tablets studied were aspirin [52], [53] and acetaminophen [54], 

Polymers or amorphous solids used as pharmaceutical excipients have been also studied by means of solid-state NMR. The investigations included celluloses [56], [57], amyloses and starches [58], [59], hydrous and anhydrous lactose [27] and cyclodextrins [58], [59], [60] — easily available natural host compounds, increasingly popular for encapsulation of drugs [61]. 

C A Fyfe, Solid State NMR for Chemists, 1983, C F C Press, Guelph, Ontario, Canada 

H Saito, M Yokoi, M Aida, M Kodama, T Oda and Y Sato, Magn Reson Chem 155-161 (1988) 

J Braun, M Schlabach, B Wehrle, M Kocher, E Vogler, H-H Limbach, JAm Chem 5oc 116, 6593-6604(1994) 

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