Structure-odor relationships

Naipawer RE, Purzycki KL, Shaffer GW, Erickson RE. A structure-odor relationship for sandalwood aroma chemicals. In Essential Oils. 1981. Mookherjhee BD, Mussinian CJ, eds. Allured, Wheaton, IL. pp. 105-133. 

Witteveen JG, van der Weerdt AJA. Structure-odor relationships of some new synthetic sandalwood aroma chemicals. Synthesis and olfactive properties in a series of bicyclo(4.4.0.decan-3-ols. Rec. Trav. Chim. Pays Bas. 1987 106 29-34. 

Chastrette M, Zakarya D, Pierre C. Structure-odor relationships in sandalwood search for an interaction model based on the concept of a santalophore superpattern. Eur. J. of Med. Chem. 1990 25 433-440. 

Zakarya, D. and Chastrette, M. (1998). Contribution of Structure-Odor Relationships to the Elucidation of the Origin of Musk Fragrance Activity. In Comparative QSAR (Devillers, J., ed.), Taylor Francis, Washington (DC), pp. 169-195. [R]... 

In addition to pharmaceutical applications, pharmacophore models have also been generated to analyze structure-odor relationships. In spite of complications arising from the need for more information on the mechanistic basis of olfaction, successful models have been developed... 

Amboni, D., de, M.C., da Silva Junkes, B., Yunes, R.A. and Heinzen, V.E.F. (2000) Quantitative structure-odor relationships of aliphatic esters using topological indices. J. Agr. Food Chem.,... 

Ivanciuc, O. (2002e) Structure-odor relationships for pyrazines with support vector machines. Internet Electron.]. Mol. Des., 1, 269-284. 

Mihara S. and Masuda H. (1988) Structure-odor relationship for disubstituted pyrazines. J. Agric. Food Chem. 36, 1242-7. 

Rognon C. and Chastrette M. (1994) Structure-odor relationships a highly predictive tridimensional interaction model for the bell-pepper note. Eur. J. Med. Chem. 29, 595-609. 

It is important to note that IR absorption spectroscopy is in fact the basis of the vibrational theory of olfactory reception. This theory has been found to be limited in terms of explaining structure-odor relationships (Rossiter 1996). First, enantiomers, molecules that form non-superimposable mirror images of each other, have identical IR absorption spectrum, yet they can smell differently, e.g., the S- and R- enantiomers... 

Rossiter, K.J. Structure-Odor Relationships. Chemical Review 96(8), 3201-3240 (1996) Sachse, S., Rappert, A., Galizia, G.C. The spatial representation of chemical structures in the antennal lobe of honeybees steps towards the olfactory code. European Journal of Neuroscience 11, 3970-3982 (1999)... 

Steroids with 0-heterocychc fragments (pyrans and 0-macroheterocycles) as bioactive metabolites from echinoderms and porifera 97G771. Structure-odor relationships 96CRV3201. 

KJ Rossiter. Structure-odor relationships. Chem Rev 96 3201-3240, 1996. PM Wise, MJ Olsson, WS Cain. Quantification of odor quality. Chem Senses 25 429 3, 2000. 

Winter, B. (2004) Spirocydic ethers related to Ambrox syntiiesis and structure-odor relationships. Helv. Chim. Acta, 87, 1616-1627. 

Quantitative Structure-Odor Relationships of Aliphatic Esters Using Topological Indices. 

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