Structure enzymology

G. J. Davies and C. Martinez-Fleites, The O-GlcNAc modification Three-dimentional structure, enzymology and the development of selective inhibitors to probe disease, Biochem. Soc. Trans., 38 (2010) 1179-1188. 

Schneider G and Lindqvist Y (2001) Structural enzymology of biotin biosynthesis. EBBS Letters 495, 7-11. 

Davies GJ, Henrissat B. Structural enzymology of carbohydrate-active enzymes implications for the post-genomic era. Biochem Soc Trans 2002 30 291-297. 

Chou P Y and G D Fasman 1978. Prediction of the Secondary Structure of Proteins from Tlieir Amino Acid Sequence. Advances in Enzymology 47 45-148. 

Tucker, P.W., Hazen, E.E., Colton, F.A. Staphylococcal nuclease reviewed a prototypic study in contemporary enzymology. III. Correlation of fhe three-dimensional structure with the mechanisms of enzymatic action. Mol. Cell. Biochem. 

T. C. Bruice and S. I Benkovic, Bioorganic Mechanisms, Vol. 1, W. A. Benjamin, New brk, 1966, pp. 1-258 W. P. Jencks, Catalysis in Chemistry and Enzymology, McGraw-Hill, New York, 1969 M. L. Bender, Mechanisms of Homogeneous Catalysis from Protons to Proteins, Wiley-Interscience, New York, 1971 C. Walsh, Enzymatic Reaction Mechanisms, W. H. Freeman, San Francisco, 1979 A. Fersht, Enzyme Structure and Mechanism, 2nd ed., W. H. Freeman, New York, 1985. 

Karger, B. L., and Fiancock, W. S., eds. 1996. Methods in Enzymology 271, Section III Protein Structure Analysis by Mass Sj ectrometry, f R. Yates P tide Characterization by Mass Spectrometry, B. L. Gillece-Castro and J. T. Stnlts. New York Academic Pre.s.s. 

Earner, J., 1990. Insulin and the stimulation of glycogen synthesis The road from glycogen structure to glycogen synthase to cyclic AMP-dependent protein kinase to insulin mediators. Advances in Enzymology 63 173-231. 

Schroeder, W. A. "Separation of Peptides by Chromatography on Columns of Dowex 1 with Volatile Developers", In "Methods In Enzymology", p. 214, Vol. XXV, "Enzyme Structure, Part B", C. H. W. Hlrs and S. N. Tlmasheff, Editors, Academic Press, New York, 1972. 

B. Botton and M. Chalot, Nitrogen assimilation Enzymology in ectomycorrhizas, Mvcorrhiza Structure, Molecular Biology and Function (A. K. Varma and B. Hock, eds.), Springer-Verlag, Berlin Heidelberg, New York, 1995, pp. 325-364. 

Bricogne. G. (1997) The Bayesian statistical viewpoint on structure determination basic concepts and examples, In Macromolecular Crystallography, Vol. 276 of Methods in Enzymology, Carter Jr., C.W. and Sweet, R.M. (Eds.), Academic Press, pp. 361 123. 

Zinc is a constituent of over 300 enzymes with much research into the coordination of zinc to the protein backbone, and how its chemistry is modulated by the donor set and environment.2 As well as the Lewis acid catalysis properties in enzymes, the structural role in zinc finger proteins has been a major area of research since the late 1990s. A number of reviews on zinc physiology, enzymology, and proteins in general have been published.978-981 There is extensive analysis available to classify the mononuclear sites in zinc proteins and identification of structural relationships of the extended environment.982,983... 

Arand, M., Cronin, A., Adamska, M. and Oesch, F. (2005) Epoxide hydrolases structure, function, mechanism, and assay, Methods in Enzymology, 400, 569-588. 

Varela, E., Guillen, F., Martinez, A.T. and Martinez, M.J. (2001) Expression of Pleurotus eryngii aryl-alcohol oxidase in Aspergillus nidulans purification and characterization of the recombinant enzyme. Biochimica et Biophysica Acta, Protein Structure and Molecular, Enzymology, 1546 (1), 107-113. 

Parise, G. and Bazzicalupo, P. (1997) Assembly of nematode cuticle role of hydro-phobic interactions in CUT-2 cross-linking. Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology 1337, 295-301. 

G.L. Peterson, Determination of total protein. In Colowick SP, Kaplan NO. Methods in Enzymology. Vol. 91 Enzyme Structure - Part I., 1987, Hirs CHW, Timasheff SN, editors. Londra Academic Press Inc. p 95-119. 

Veronese FM, Caliceti P, Schiavon O (1997) Branched and linear poly(ethylene glycol) Influence of the polymer structure on enzymological, pharmacokinetic and immunological properties of proteinconjugates. J Bioact Compatible Polym 12 196-207... 

Enzymology and Structure of Catalases Peter Nicholls, Ignacio Fita, and Peter C. Laewen... 

Structure and Enzymology of Diheme Enzymes Cytochrome cdy Nitrate and Cytochrome c Peroxidase Vilmos Fiilop, Nicholas J. Watmough, and Stuart J. Ferguson... 

Rees, D.C. (2002) Great metalloclusters in enzymology, Anna. Rev. Biochem., 71, 221-246. Sazinsky, M.H. and Lippard, S.J. (2006) Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins, Acc. Chem. Res., 39, 558-566. 

The mechanism that is consistent with biochemical, enzymological and structural data involves binding of arginine, in which the side-chain of Glu277 plays an important role, attack of the nucleophilic metal-bridged hydroxyl ion, formation of a neutral, tetrahedral intermediate which is stabilized by the dinuclear Mn(II) centre, and finally proton transfer from Hisl41, followed by release of the two products (Figure 16.5). 

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