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Structural Requirements for Targeting Absorptive Intestinal Transporters

Structural Requirements for Targeting Absorptive Intestinal Transporters [Pg.245]

A lot of structure-activity information has been accumulated over the last two decades for various intestinal transporters. However, the two most studied transporters in terms of quantitative structure-activity relationship (QSAR) are SLC15A1 [74—80] and ABCB1 (for references see Ref. [81]), which will be the topic of Chapter 18. In the following section, the focus will be on strategies for increasing intestinal absorption of dmg candidates by targeting intestinal peptide transporters. [Pg.245]


Structural Requirements for Targeting Absorptive Intestinal Transporters 245... [Pg.245]




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Absorptive intestinal transporter

Intestinal transport

Intestinal transporters

Intestine absorption

Intestines, structure

Structural requirements

Structural requirements for

Target structure

Targets transporters

Transport structure

Transporters intestinal absorption

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