Striatum cholinergic innervation

Cholinergic innervation of the human striatum, globus pallidus, subthalamic nucleus, substantia nigra, and red nucleus. J. Comp. Neurol. 323,252-268. 

Gerfen, 2004). The patch compartments of the striatum are characterized by low levels of acetylcholine and high levels of various opiates and substance P. The matrix compartment is characterized by cholinergic and somatostatin-containing neurons. Anatomically, corticostriatal and thalamostriatal projections are closely associated with the striatal matrix, while projections from limbic structures, such as the hippocampus and the amygdala, primarily innervate striatal patches. 

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