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Striatal dopaminergic receptor

Photoaffinity Labeling of Striatal Dopaminergic Receptor Sites by Chlorpromaz ine... [Pg.138]

Administrations of five injeetions of METH (15 mg/4cg/injection 6-hour intervals between injections) caused substantial increases in the striatal and nigral levels of all three neuropeptides examined in rats sacrificed 18 hours following treatment. Figures 1 to 3 present the effects of blocking the Dj and D2 dopaminergic receptors on the responses by these peptide systems... [Pg.261]

Matarredona E. R., Santiago M., Venero J. L., Cano J., and Machado A. (2001). Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction. J. Neurochem. 76 351-360. [Pg.197]

Cycleanine Binds to dopaminergic receptors less strongly than dauricine and cepharanthine inhibited binding of [3H]spiperone to rat striatal membranes 626,627... [Pg.200]

Jung AB, Bennett JP, Jr. 1996. Development of striatal dopaminergic function. I. Pre- and postnatal development of mrnas and binding sites for striatal D1 (dla) and D2 (d2a) receptors. Dev Brain Res 94 109-120. [Pg.228]

Pyridoxal phosphate enzymes have been targets of therapeutic interventions. Abnormal pulsatile stimulation of striatal dopamine receptors leads to dysregnla-tion of genes and proteins in downstream nenrons and, conseqnently, alterations in neuronal firing patterns. These result in the motor complications associated with Parkinson s disease. Treatment of Parkinson s disease aims to restore normal dopaminergic transmission at striatal synapses. Levodopa slows the progression of Parkinson s disease and has a prolonged effect on the symptoms of the disease. [Pg.199]

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Dopaminergic

Dopaminergic receptors

Dopaminergics

Striatal dopaminergic receptor sites

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