Streptomyces scabies

Streptomyces scabies esterase (lESC) [53] Serl4 Serl4 Gly66 Asnl06 ND2 ... 

Bacteria Bacillus megaterium Serratia marcescens Staphylococcus albus Streptomyces scabies Rod-shaped Rod-shaped Spherical Filamentous 2.8-1.2-1.5//m 0.7-1.0 x 0.7 pm 1.0 pm 0.5-1.2 pm dia... 

Lapwood, D.H., Wellings, L.W., Hawkins, J.H. Irrigation as apractical means to control potato common scab (Streptomyces scabies) final experiment and conclusions. Plant Pathol 1973 22 35-41. 

Oestergaard, S.P., Nielsen, S. Control of potato scab (Streptomyces scabies) by irrigation. Tidsskrift for Planteavl 1979 83 201-204. 

Sturz, A.V., Ryan, D.A.J., Matheson, B.G, Arsenault, W.J., Kimpinski, J., Christie, B.R. Stimulating disease suppression in soils sulphate fertilizers can increase biodiversity and antibiosis ability of root zone bacteria against Streptomyces scabies. Soil Biol Biochem 2004 36 343-352. 

Streptomyces pathogens are quite rare in plant diseases. Thaxtomin A from Streptomyces scabies causes scab disease of potato, which is characterized by conspicuous corky lesions on tubers. Molecular genetic investigation has revealed that thaxtomins are biosynthesized by nonribosomal peptide synthetases (txtAB) that condense modified L-phenylalanyl and L-4-nitrotryptophanyl units to form a 2,5-dioxopiperazine skeleton.316 Disruption of txtA results in the formation of nonpathogenic strain. This toxin is shown to affect the movement of calcium ions and protons across the plasma membrane and also inhibit cellulose biosynthesis.317... 

Properties Fusarium solani pisi 1 11 Fusarium roseum culmorum Fusarium roseum sambucirnum Vlocladium consortiale Streptomyces scabies Helminthosporum sativum ... 

King RR, Lawrence CH, Calhoun LA. 1998. Unusual production of 5-nitroanthranilic acid by Streptomyces scabies. Phytochemistry 49 1265-1267. 

During a survey of actinobacteria known to suppress the growth of Streptomyces scabies, the causative agent of potato scab disease, a series of six new phenazine alkaloids were isolated and characterized by Salomon and coworkers [95]. NMR analysis of the ethyl acetate and butanol extracts of the culture supernatant and mycelium suggested a suite of aromatic compounds that were ultimately determined to be glycosylated 1,6-disubstituted phenazines (107—112). The structure of the phenazine and the various substituents that were substituted at the 1- and 6-positions are shown below. The structures of these phenazines, with the exception of 111, are the first examples of diglycosylated phenazine alkaloids. 

---